Article information

2006 , Volume 11, ¹ 5, p.41-54

Klishevich M.A., Kogai V.V.

Study of cyclic regulatory circuits of gene networks with negative type of regulation

The core of gene networks (GN) is regulatory circuits - genes and proteins with mutually regulated expression. Thus, detection of possible operation modes of regulatory circuits is an important problem of systems biology. The work presents an efficient method for computing symmetric periodic solutions for cyclic regulatory circuits for M(n,2) model.

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Author(s):
Klishevich Mikhail Aleksandrovich
Office: Sobolev Institute of Mathematics of SB RAS
Address: 630090, Russia, Novosibirsk
Phone Office: (383) 333-33-87
E-mail: mans1@ngs.ru

Kogai Vladislav Vladimirovich
PhD.
Position: Senior Research Scientist
Office: Sobolev Institute of Mathematics of SB RAS
Address: 630090, Russia, Novosibirsk, Prospekt Academika Koptyga, 4
Phone Office: (383) 363-46-95
E-mail: kogai@math.nsc.ru


Bibliography link:
Klishevich M.A., Kogai V.V. Study of cyclic regulatory circuits of gene networks with negative type of regulation // Computational technologies. 2006. V. 11. ¹ 5. P. 41-54
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