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Инд. авторы:	Grishin O.V., Gultyaeva V.V., Uryumtsev D.Y., Zinchenko M.I., Grishin V.G.
Заглавие:	Diagnostic use of the resistive device in copd patients
Библ. ссылка:	Grishin O.V., Gultyaeva V.V., Uryumtsev D.Y., Zinchenko M.I., Grishin V.G. Diagnostic use of the resistive device in copd patients // International conference on biomedical engineering and computational technologies (SIBIRCON): Сonference proceedings. - 2015: The Institute of Electrical and Electronics Engineers (IEEE). - P.146-149. - ISBN: 978-1-4673-9109-2.
Внешние системы:	DOI: 10.1109/SIBIRCON.2015.7361871; РИНЦ: 27153644; РИНЦ: 25051735; SCOPUS: 2-s2.0-84969242467; WoS: 000380436300033;
Реферат:	eng: INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is diagnosed in later or very advanced stages. The aim of the study was to evaluate feasibility of low respiratory resistive load (LRRL) in patients with COPD for a new objective method of early COPD diagnostics and to examine changes in pulmonary gas exchange during LRRL. METHODS: The study involved eleven patients with mild or moderate COPD and fourteen healthy adult volunteers. After anthropometric and spirometric measuring, pulmonary gas exchange was measured for 7 minutes using the breath-by-breath method under two conditions: 1) without respiratory resistive load (WRL); 2) with LRRL 0.4 cm H2O ∙ l‒1 ∙ s. Valve system (Intersurgical, UK) was used as a resistive device. RESULTS: Decrease in oxygen consumption (VO2) and carbon dioxide production (VCO2) during LRRL was significantly greater in COPD patients than in healthy subjects (14 vs. 8 %, p<0.009 and 16 vs. 10 % , p<0.020 respectively). In contrast, tidal volume increased by 13 % in healthy subjects only. CONCLUSION: Pulmonary gas exchange shift during low respiratory resistive load appears to be a feasible criterion of early COPD diagnostics. Future research is needed to examine sensitivity and specificity of the method.
Ключевые слова:	resistive device; pulmonary gas exchange; respiratory resistive load; chronic obstructive pulmonary disease;
Издано:	2015
Физ. характеристика:	с.146-149
Цитирование:	1. Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease, 2014. 2. Carlone S., Balbi B., Bezzi M., Brunori M., Calabro S., Barbaro M.P.F., Micheletto C., Privitera S., Torchio R., Schino P. and Vianello A., “Health and social impacts of COPD and the problem of under-diagnosis,” Multidiscip. Respir. Med,” vol. 9 (1), p. 63, December 2014. 3. Petty T.L., “Definitions, causes, course, and prognosis of chronic obstructive pulmonary disease,” Respir. Care Clin. N. Am., vol. 4 (3), pp. 345-358, September 1998. 4. Rudolf M., “The reality of drug use in COPD: the European perspective,” Chest, vol. 117 (2 Suppl), pp. 29S-32S, February 2000. 5. Shahab L., Jarvis M.J., Britton J. and West R., “Prevalence, diagnosis and relation to tobacco dependence of chronic obstructive pulmonary disease in a nationally representative population sample,” Thorax, vol. 61 (12), pp. 1043-1047, December 2006. 6. Parshall M.B., Schwartzstein R.M., Adams L., Banzett R.B., Manning H.L., Bourbeau J., Calverley P.M., Gift A.G., Harver A., Lareau S.C., Mahler D.A., Meek P.M. and O'Donnell D.E., “An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea,” Am. J. Respir. Crit. Care Med., vol. 185 (4), pp. 435-452, February 2012. 7. Gottfried S.B., Altose M.D., Kelsen S.G., Fogarty C.M. and Cherniack N.S., “The perception of changes in airflow resistance in normal subjects and patients with chronic airways obstruction,” Chest, vol. 73(2 Suppl), pp. 286-288, February 1978. 8. Boer L.M., Asijee G.M., van Schayck O.C. and Schermer T.R., “How do dyspnoea scales compare with measurement of functional capacity in patients with COPD and at risk of COPD?” Prim. Care Respir. J., vol. 21 (2), pp. 202-207, June 2012. 9. Grishin O.V., Uryumtsev D.Yu. and Grishin V.G., “Changes in pulmonary gas exchange during resistive loading that do not cause a sense of shortness of breath,” Hum. Physiol., vol. 40 (1), pp. 87-90, July-August 2014 . 10. Bader N., Bosy-Westphal A., Dilba B. and Müller M.J., “Intra-and interindividual variability of resting energy expenditure in healthy male subjects -biological and methodological variability of resting energy expenditure,” Br. J. Nutr., vol. 94 (5), pp. 843-849, November 2005. 11. Wiley R.L. and Zechman F.W, “Perception of added airflow resistance in humans,” Respir. Physiol., vol. 2 (1), pp. 73-87, December 1966. 12. Davenport P.W., Chan P.Y., Zhang W. and Chou Y.L., “Detection threshold for inspiratory resistive loads and respiratory-related evoked potentials,” J. Appl. Physiol., vol. 102 (1), pp. 276-285, January 2007. 13. Zechman F.W. and Davenport P.W., “Temporal differences in the detection of resistive and elastic loads to breathing,” Respir. Physiol., vol. 34 (2), pp. 267-277, August 1978. 14. Louhevaara V.A., “Physiological effects associated with the use of respiratory protective devices,” Scand. J. Work. Environ. Health., vol. 10 (5), pp. 275-281, October 1984. 15. Jones G.L., Killian K.J., Summers E. and Jones N.L., “Inspiratory muscle forces and endurance in maximum resistive loading,” J. Appl. Physiol., vol. 58 (5), pp. 1608-1615, May 1985. 16. Hochachka P.W., “Intracellular convection, homeostasis and metabolic regulation,” J. Exp. Biol., vol. 206 (pt 12), pp. 2001-2009, June 2003. 17. Mortola J.P., “Implications of hypoxic hypometabolism during mammalian ontogenesis,” Respir. Physiol. Neurobiol., vol. 141 (3) pp. 345-356, August 2004. 18. Mortola J.P. and Maskrey M., “Metabolism, temperature, and ventilation,” Compr. Physiol., vol. 1 (4), pp. 1679-1709, October 2011.